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Immunopolymorphism Database

Moredun's MHC defined flock comprises animals homozygous for one of four common MHC haplotypes along with a large number of matched MHC heterozygous animals.  Each of the MHC haplotypes has been extensively characterised at the genetic level with the important MHC class I and class II genes cloned, sequenced and expressed. 

These sequences have provided the reference sequences for populating the sheep section of the immunopolymorphism database.  This public database provides a source of information on MHC genetic diversity in domestic sheep. Its purpose is to collate data on allelic diversity and provide a forum for the analysis, verification and nomenclature of diversity in the genes and proteins of the ovine MHC.

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Printed from http://www.moredun.org.uk/research/expertise-%40-moredun/immunology/mhc-defined-flock/immunopolymorphism-database on 30/03/17 11:32:44 AM

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