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Professor Gary Entrican

Professor Gary Entrican
Address: 

Moredun Research Institute
Pentlands Science Park
Bush Loan
Penicuik
Midlothian EH26 0PZ
Scotland

Telephone Number: 
+44 (0)131 445 5111
Email address: 

gary.entrican@moredun.ac.uk

Gary Entrican is a Principal Research Scientist at Moredun and holds an Honorary Professorship within the College of Medicine and Veterinary Medicine, University of Edinburgh. He is also Honorary Clinical Associate Professor within the College of Medical, Veterinary and Life Sciences at University of Glasgow.

He graduated with BSc Hons in Immunology from University of Glasgow, where he also conducted his PhD in Immunology. He joined Moredun in 1986 working on immune regulation in sheep and has applied his immunological skills to studies on causes of infectious abortion in sheep, initially on Border Disease Virus and more recently on Chlamydia abortus.

Gary's immunological skills are in the areas of ruminant cellular immunology, cytokine biology and the understanding of host-pathogen interactions during infection. The ultimate aim of his research is to identify immunological correlates of protection that underpin vaccine design and implementation of disease control strategies. He has established competitively-funded research links with colleagues at University of Edinburgh.  He led a BBSRC/Bio-Rad AbD Serotec-funded Industrial Partnership Award on identification of immune correlates in sheep and cattle with The Roslin Institute at The University of Edinburgh.  The outputs of this project were summarised in a webinar delivered under the auspices of Bio-Rad AbD Serotec in July 2015.  This webinar is now available here

Gary was appointed Chair of the International Union of Immunological Societies (IUIS) Veterinary Immunology Committee (VIC) in 2013.  This committee unites the global veterinary immunology community to create a network of expertise, and also supports meetings and workshops.  Further information about IUIS VIC can be found here.

Gary is a member of the Steering Committee of the BBSRC UK Veterinary Vaccinology Research Network, which aims to facilitate collaborations and formulate strategies that address unmet needs in veterinary vaccine development.   

Current Research: 
  • Investigation of innate and adaptive immune responses to Chlamydia abortus infection for implementation of disease prevention and control. Scottish GovernmentRESAS Programme Funding, Theme 6 (2011-16). 
  • Inflammasome activation in ruminant cells infected withChlamydia abortus. BBSRC/Zoetis CASE PhD Studentship (Laura Doull) within EBRC and University of Edinburgh (2011-15). Collaborative project with Roslin Institute (Prof Liz Glass).
  • Neonatal vaccination: role for innate immune cell interactions in BCG vaccination. BBSRC/Zoetis CASE PhD Studentship (Carly Hamilton) within EBRC and University of Edinburgh. Collaborative project with Roslin Institute (Dr Jayne Hope). 
  • The Role of Dendritic Cells in the Pathogenesis of Bluetongue. WB Martin PhD Studentship (Eleonora Melzi) between Moredun and University of Glasgow (2012-2015). Collaborative project with University of Glasgow (Prof Massimo Palmarini). Other Moredun Investigator: Dr Mara Rocchi.
  • Activation of immune responses using ovine lentivirus vaccine vectors. Moredun Scientific PhD Studentship (Rebecca McLean) led by Dr David Griffiths (Moredun) and collaborative with University of Edinburgh (Dr Jayne Hope) (2013-2016).
  • Does Chlamydia trachomatis infection have a causative role in miscarriage? Tommy’s Studentship (Sevasti Giakoumelou) with University of Edinburgh (2012-2015). Collaborative Project with QMRI, University of Edinburgh (Dr Andrew Horne and Prof Sarah Howie). 
  • Understanding inflammatory processes in ovine footrot to inform rational vaccine design. BBSRC Animal Health Research Club (2015-2018). Collaborative Project with University of Nottingham (Dr Sabine Totemeyer, Prof Richard Emes, Dr Tracy Coffey and Dr Jasmeet Kaler).

A selection of Gary's publications can be seen below or for a complete list of papers published since 2010 please click here.

Selected Key Publications

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Printed from http://www.moredun.org.uk/staff/professor-gary-entrican on 25/06/17 01:14:23 PM

Moredun is committed to promoting animal health and welfare through research and education and is recognized worldwide for its contribution to research into infectious diseases of farmed livestock.