Gamma Interferon Fails To Induce Expression of Indoleamine 2,3-Dioxygenase and Does Not Control the Growth of Chlamydophila abortus in BeWo Trophoblast Cells
Is Part of:
Infection and Immunity, 70, 5, pp2690-2693.
Abstract:
ABSTRACT
The BeWo trophoblast cell line does not constitutively express the tryptophan degrading enzyme indolamine 2,3-dioxygenase (IDO), nor can IDO expression be induced by gamma interferon. This correlates with the inability of BeWo cells to control the growth of
Chlamydophila abortus
, in contrast to effects observed in HeLa cells treated with gamma interferon.