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Typing of Pasteurella multocida Isolated from Pigs with and without Porcine Dermatitis and Nephropathy Syndrome

Published: 2002

Research Scotland: 20.500.12594/11789


  • F. A. Lainson

  • K. D. Aitchison

  • W. Donachie

  • J. R. Thomson

Is Part of:

Journal of Clinical Microbiology, 40, 2, pp588-593.



Porcine dermatitis and nephropathy syndrome (PDNS) is a sporadic, usually fatal disease of growing and finishing pigs that has been recognized in many pig-producing countries.
Pasteurella multocida
strains isolated from 15 pigs with PDNS and 51 pigs without PDNS were characterized by capsule and somatic antigen typing, random amplified polymorphic DNA (RAP-D) typing, and restriction analysis of genomic DNA using pulsed-field gel electrophoresis (PFGE). While capsular, somatic, and RAP-D typing did not discriminate PDNS isolates from non-PDNS isolates, all of the isolates from PDNS cases showed an identical
I PFGE restriction pattern. This pattern was also found in a high proportion (36%) of
P. multocida
strains isolated from non-PDNS cases. Isolation of a single variant of
P. multocida
from tissues of pigs with PDNS warrants further investigation into the possible role of these bacteria in the etiology of the disease.

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